The "hardware, software, facilities, data, and personnel" needed "to achieve the most cost-effective system for satisfying [an] organization's [information] needs." Source: U.S. Government Accounting Office, Strategic Information Planning, Framework for Designing and Developing System Architectures, archive.gao.gov/d32t10/146630.pdf, June 1992. In the PEPFAR context, an SIS uses data from Surveys and Surveillance, Monitoring and Evaluation, and Health Management Information Systems (HMIS) to produce strategic information (SI).
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